Methodological quality of clinical trials of keloid scars

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Methodological quality and reporting of ethical requirements in clinical trials.

OBJECTIVES To assess the relationship between the approval of trials by a research ethics committee (REC) and the fact that informed consent from participants (ICP) was obtained, with the quality of study design and methods. DESIGN Systematic review using a standardised checklist. MAIN MEASURES Methodological and ethical issues of all trials published between 1993 and 1995 in the New Englan...

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Keloid Scars: The Hidden Burden of Disease

Background: Keloid scar patients are known to present with a combination of symptoms including pain, physical deformity and psychological distress. These three facets that characterise the full extent of the keloid disease (KD) have not been validated in a clinical setting before as a whole and thus the disease is usually approached and managed incompletely. Assessment measures need to accurate...

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Prevention and management of keloid scars.

A 31-year-old woman, gravida 3, para 2, at 30 weeks of gestation was referred to our institution with the symptom of rapid growth of her keloid scars during her current pregnancy. She was black and had a surgical history of a cesarean delivery and a right vulvar excision for a benign inclusion cyst. The keloid scarring was present at her pfannenstiel incision and also at the site of her right v...

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A Case of Multiple Spontaneous Keloid Scars

Keloid scars result from an abnormal healing response to cutaneous injury or inflammation that extends beyond the borders of the original wound. Spontaneous keloid scars forming in the absence of any previous trauma or surgical procedure are rare. Certain syndromes have been associated with this phenomenon, and few reports have discussed the evidence of single spontaneous keloid scar, which rai...

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Evaluation of Clinical Trials

In a number of important clinical issues such as evaluation of the efficacy or effectiveness of therapeutic or preventive interventions as well as for comparing the harms of interventions, randomized controlled trials (RCTs) provide the highest levels of evidence, either directly or indirectly. It is obvious that critical appraisal of these studies to assess their validity and precision is of p...

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ژورنال

عنوان ژورنال: Cirugía y cirujanos

سال: 2023

ISSN: ['2444-0507']

DOI: https://doi.org/10.24875/cirue.m22000172